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Mutations of Odontogenesis-Associated Phosphoprotein (ODAPH, OMIM *614829) cause autosomal recessive amelogenesis imperfecta, however, the function of ODAPH during amelogenesis is unknown. Here we characterized normalOdaphexpression by in situ hybridization, generatedOdaphtruncation mice using CRISPR/Cas9 to replace the TGC codon encoding Cys41 into a TGA translation termination codon, and characterized and compared molar and incisor tooth formation inOdaph^+/+,Odaph^+/C41*, andOdaph^C41*/C41*mice. We also searched genomes to determine when Odaph first appeared phylogenetically. We determined that tooth development inOdaph^+/+andOdaph^+/C41*mice was indistinguishable in all respects, so the condition in mice is inherited in a recessive pattern, as it is in humans.Odaphis specifically expressed by ameloblasts starting with the onset of post-secretory transition and continues until mid-maturation. Based upon histological and ultrastructural analyses, we determined that the secretory stage of amelogenesis is not affected inOdaph^C41*/C41*mice. The enamel layer achieves a normal shape and contour, normal thickness, and normal rod decussation. The fundamental problem inOdaph^C41*/C41*mice starts during post-secretory transition, which fails to generate maturation stage ameloblasts. At the onset of what should be enamel maturation, a cyst forms that separates flattened ameloblasts from the enamel surface. The maturation stage fails completely.

Single crystal microwires of a well‐studied organic semiconductor used in organic solar cells, namelyp‐DTS(FBTTh₂)₂, are prepared via a self‐assembly method in solution. The high level of intermolecular organization in the single crystals facilitates migration of charges, relative to solution‐processed films, and provides insight into the intrinsic charge transport properties ofp‐DTS(FBTTh₂)₂. Field‐effect transistors based on the microwires can achieve hole mobilities on the order of ≈1.8 cm²V⁻¹s⁻¹. Furthermore, these microwires show photoresponsive electrical characteristics and can act as photoswitches, with switch ratios over 1000. These experimental results are interpreted using theoretical simulations using an atomistic density functional theory approach. Based on the lattice organization, intermolecular couplings and reorganization energies are calculated, and hole mobilities for comparison with experimental measurements are further estimated. These results demonstrate a unique example of the optoelectronic applications ofp‐DTS(FBTTh₂)₂microwires.